Purpose. To present a rare clinical observation – secondary lesion of the pericardium in ovarian cancer.

Materials and methods. A clinical observation of a 64-year-old female patient Z. with clinical signs of cardiac tamponade, with complaints of shortness of breath when walking up to 10 meters and lying down, with paroxysmal dry cough with recurrent urge to vomit, edema of the lower extremities is presented. From the anamnesis it is known that the patient has ovarian cancer (serous adenocarcinoma GIII) with metastases in the peritoneum, omentum with invasion of the small intestine and its mesentery, metastases in the peri-pectoral lymph nodes. The patient underwent a comprehensive examination: echocardiography, MSCT of the chest, MRI of the heart with contrast.

Results. The possibilities of imaging research methods for metastatic lesions of the pericardium in a patient with ovarian cancer are described. The diagnosis was verified by cytological examination of the pericardial effusion.

Conclusion. Pericardial metastatic disease is a rare manifestation of atypical metastasis of ovarian cancer. Multimodal imaging in the diagnosis of secondary lesions of the heart and pericardium allows obtaining complete diagnostic information about the location and size of the tumor, which determines the further tactics of patient management.