Nephroscintigraphy in assessing the functional state of the renal parenchyma in the surgical treatment of coral nephrolithiasis

Chekhonatskaya M.L., Rossolovsky A.N., Kryuchkov I.A., Nikolenko V.N., Bobylev D.A., Velikanova M.G., Kondrat’eva O.A., Chekhonatsky I.A.

Purpose. To assess the functional state of renal parenchyma in patients with coral nephrolithiasis before and after surgery by determining the effective renal plasma flow and the level of β2-microglobulinuria. Materials and methods. The study involved 94 patients with an established diagnosis of urolithiasis, with coralloid calculi K1-K3 renal localization. All patients underwent a complex of instrumental and laboratory studies, radionuclide study. Surgical treatment was performed by percutaneous nephrolithotripsy (PNLT). Results. In this study, a direct correlation between the value of effective renal plasma flow and β2-microglobulinuria in patients with ICD in the perioperative period was revealed. The results of the study showed that the value of effective renal plasma flow of the kidney in the group of patients with residual nephrolithiasis was lower than in patients without concrement. Conclusion. Residual renal calculi, which are not susceptible to conservative therapy for 3 months, after PNLT have a damaging effect on the renal parenchyma, which is expressed in a decrease in the effective renal plasma flow and an increase in the level of urine β2-microglobulin compared with the control group.	1 - V.I. Razumovsky Saratov State Medical University. Saratov, Russia. 2 - I.M. Sechenov First Moscow State Medical University (Sechenov University). Moscow, Russia. 3 - M.V. Lomonosov Moscow State University. Moscow, Russia. 4 - S.R. Mirotvortsev Clinical hospital. Saratov, Russia. 5 - Russian Medical Academy of Postgraduate Education. Moscow, Russia.

 

Keywords: urolithiasis, radionuclide diagnosis, percutaneous nephrolithotripsy, residual concretions, urine β2-microglobulin.

Corresponding author:  Kryuchkov I.A., e-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript

 

For citation: Chekhonatskaya M.L., Rossolovsky A.N., Kryuchkov I.A., Nikolenko V.N., Bobylev D.A., Velikanova M.G., Kondrat’eva O.A., Chekhonatsky I.A. Nephroscintigraphy in assessing the functional state of the renal parenchyma in the surgical treatment of coral nephrolithiasis. REJR 2019; 9(3):134-142. DOI:10.21569/2222-7415-2019-9-3-134-142.

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Received:        24.06.19 Accepted:       11.07.19