Lacrimal gland carcinoma: efficancy of combined treatment and prognoses.

Saakyan S.V., Amiryan A.G., Valskiy V.V., Mironova I.S., Maybogin A.M.

Purpose. To determine the efficiency of treatment and to assess the vital prognosis of patients with carcinoma of the lacrimal gland (LGC) in long-term follow-up.	Moscow Helmholtz Research Institute of Eye Diseases. Moscow, Russia.

 

 

 

 

 

 

 

 

 

Materials and methods. 26 patients (17 women, 9 men) aged 10 to 69 years (mean - 38,9 ± 14,9 years) with LGC were treated. All the patients underwent a complete clinical - instrumental examination, the diagnosis of LGC confirmed morphologically after surgery. Follow-up was from 13 to 204 months (median - 22.5 months) after surgery. Results. In 3 patients tumor stabilization was estimated, the others - various lo-cal/regional recurrences were identified. It had been shown that the basaloid subtype of ad-enocystic LGC prognostically was the most unfavorable. Distant metastases were found in 9 patients, 4 of them died (median follow up - 22.5 months). Conclusion. The efficiency of LGC treatment remains low with high risk of local and regional recurrence. Prognosis of LGC depends on several factors, including the histological type of the tumor, the presence of perineural invasion and, possibly, on the patient’s age.

 

Keywords: lacrimal gland tumors, the lacrimal gland cancer, lacrimal gland carcinoma treatment, prognosis

 

Corresponding author:Amiryan A.G., e-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript

 

For citation: Saakyan S.V., Amiryan A.G., Valskiy V.V., Mironova I.S., Maybogin A.M. Lacrimal gland carcinoma: efficancy of combined treatment and prognoses. REJR. 2017; 7 (2):8-20. DOI:10.21569/2222-7415-2017-7-2-8-20./em>

Received: 29.03.2017 Accepted:05.05.2017