Сomputed tomography in the dynamics of pneumoconiosis.

Kovaleva A.S., Serova N.S., Bukhtiyarov I.V., Egorova E.M., Semyonova M.S.

Рurpose. To determine the role of MSCT in the development of pneumoconiosis. Materials and methods. A total of 109 patients with the pneumoconiosis: silicosis and pneumoconiosis from mixed dust were examined at the Clinical IRIOH (Moscow) and the Orenburg Regional Clinical Hospital №2 (Orenburg). Patients underwent complex clinical and laboratory research, external respiration function examination, bronchoscopy and radi-ation examination. Results. Concomitant pulmonary tuberculosis was detected in 11%. Dissemination and interstitial changes were determined. Foci were located chaotically, perilymphatically. At the time of the initial study, the fusion of foci was 67.5%, with a dynamic study - in 100%. Interstitial changes were characterized by thickening of intra-lobular and interlobular inter-stitium. 19 patients had fibrous conglomerates, which were heterogeneous due to the pres-ence of calcifications, necrosis and sometimes destruction cavities, which were later replaced by fibrotic changes. 57 patients were observed in dynamics during 3-19 years. 44 patients had a negative dynamics. There was no connection with the experience in the conditions of the impact of aerosol and profession. A great influence was exerted by the dispersion of dust and the concentration of silicon dioxide in it. Progression was characterized by an increase in the number of foci, their size, fusion and formation of fibrosis areas, an increase in the thickness of interstitium
1 - Izmerov Research Institute of Occupational Health. Moscow, Russia. 2 - I.M. Sechenov First Moscow State Medical University (Sechenov University). Moscow, Russia. 3 - Orenburg Regional Clinical Hospital №2. Orenburg, Russia.



Keywords: pneumoconiosis, dynamic observation, computed tomography.


Corresponding author:Kovaleva A.S, e-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript

For citation:Kovaleva A.S., Serova N.S., Bukhtiyarov I.V., Egorova E.M., Semyonova M.S. Сomputed to-mography in the dynamics of pneumoconiosis. REJR 2018; 8(4):95-102. DOI:10.21569/2222-7415-2018-8-4-95-102.

Received: 17.09.18 Accepted: 10.10.18