CLINICAL CASE OF NONSPECIFIC 68GA-PSMA FOCAL UPTAKE IN THE BRAIN OF A PATIENT WITH INTRACEREBRAL HEMATOMA AND PROSTATIC CANCER
Lahina Yu.S., Gulyaev D.A., Mitrofanova L.B., Ryzhkova D.V.
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Purpose. To demonstrate the clinical case of nonspecific 68Ga-PSMA uptake into non-tumor intracerebral hematoma in patient with prostatic cancer. Material and methods. A clinical case of 70-year-old patient with prostate cancer, who was hospitalized with intracerebral hematoma, suspected as hemorrhage into cerebral metastasis of prostatic cancer. Results and discussion. The clinical case has been demonstrated a false-positive uptake of 68Ga-PSMA in non-tumor intracerebral hematoma in a patient with prostate cancer. Angiogenesis with vascular proliferation and macrophage infiltration in the tissues surrounding the intracerebral hematoma are the most likely causes of nonspecific focal uptake of 68Ga-PSMA in the brain. Conclusion. Knowing the causes of non-specific uptake of 68Ga-PSMA, which may lead to false-positive results PET/CT, is important for nuclear medicine physicians. |
V.A. Almazov National Medical Research Center. Saint Petersburg, Russia. |
Keywords: intracerebral hematoma, nonspecific uptake of 68Ga-PSMA, prostate cancer, 68Ga-PSMA PET/CT false-positive results.
Corresponding author: Lahina Y. S., e-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript
For citation: Lahina Yu.S., Gulyaev D.A., Mitrofanova L.B., Ryzhkova D.V. Clinical case of nonspecific 68GA-psma focal uptake in the brain of a patient with intracerebral hematoma and prostatic cancer. REJR 2020; 10(3):179-184. DOI:10.21569/2222-7415-2020-10-3-179-184.
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Received: 11.04.20 Accepted: 19.08.20