Bykov M.V.1,4,5, Madorsky K.S.2, Semenov N. Yu. 3, Zubareva E.A.1, Marushchak E.A.1,7, Bagaev V.G.2, Lazarev V.V.1, Krylova A.A.5, Mayorov A.D.6

Purpose. To draw the attention of specialists to the question of incidence of catheter-associated and catheter-induced thrombosis in patients in intensive care units. To assess methods of visualization and monitoring of the great veins state using ultrasound. To evaluate various links in the pathogenesis of thrombus formation and the possibilities of prevention and treatment.

Materials and methods. More than 3500 ultrasound examinations have been performed in over 850 patients, both in the ICU and after the transfer of patients to specialized departments. The study included children aged from 1,5 months to 18 and adults, with one or more central venous catheters (CVCs). In the absence of contraindications, patients received prophylactic anticoagulant therapy (heparin at a dose of 50-100 U/kg/day). Ultrasound was performed with a frequency of 4 to 85 times in one patient, depending on the detection and severity of CAT. The studies were carried out in B-mode using color and/or energy mapping on ultrasound scanners Philips HD 11 (Philips, USA), SonoSite MicroMaxx (USA), Logiq E8 (GE, USA), Mindrey M 7 (Mindrey, China), Samsung HM 70 (Samsung, South Korea) using linear multi-frequency sensors 10-16 MHz.

The patients underwent a complex ultrasound examination of the superior or inferior vena cava (depending on the assumed main vein thrombosis (TMV) localization), as well as the main veins of the extremities.

Conclusions. The multifactorial nature of TMV development in ICU patients requires increased alertness to this complication, which necessitates ultrasound monitoring of the great veins in patients in intensive care units with installed CVCs. It should be noted that, despite the ongoing prophylaxis of TMV (including the use of anticoagulants), there is still a high risk of their development.


1 - N.I. Pirogova Russian National Research

Medical University.

2 - Moscow Scientific Research Institute of Emergency Pediatric Surgery and T


3 - Moscow State Budgetary Healthcare Institution Morozovskaya

Children's Clinical


4 - Central Research Institute of Epidemiology of Rospotrebnadzor.

5 - Moscow, Infectious Clinical Hospital No. 2.

6 - GBUZ MO MOZOMD. Lyubertsy, Russia.

7 - Central Clinical

Hospital of the Russian Academy of Sciences.


Keywords: ultrasound diagnostics, intensive care, catheter-associated thrombosis.


Corresponding author:  Bykov M. V., e-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript


For citation: Bykov M.V., Madorsky K.S., Semenov N. Yu., Zubareva E.A, Marushchak E.A., Bagaev V.G., Lazarev V.V, Krylova A.A., Mayorov A.D. Main vein thrombosis in the practice of an intensive care doctor. REJR 2021; 11(1):151-160. DOI: 10.21569/2222-7415-2021-11-1-151-160.


Received:       07.11.20 Accepted:     04.02.21