AUTOIMMUNE HYPOPHISITIS: THE ROLE OF MAGNETIC RESONANCE IMAGING IN THE DIAGNOSIS AND MONITORING OF THE DISEASE

 

Surovcev E.N.1,2, Kapishnikov A.V.1, Pyshkina Yu.S.1, Palamarja S.A.1

 

1 - Samara State Medical University. Samara, Russia.

2 - Berezin Sergey Medical Institute. Tolyatti, Russia.

 

 

Purpose. To analyze the value of magnetic resonance imaging (MRI) for the detection and monitoring of autoimmune hypophysitis.

Materials and methods. Clinical observation of a patient with autoimmune hypophysitis is present-ed. Conducted a comparative analysis of a series of magnetic resonance studies during dynamic ob-servation.

Results. The primary MRI study revealed: an unexpressed increase in the MR signal on T2- weighted images from the substance of the pituitary gland, its heterogeneous contrasting in the cen-tral sections at the onset of the disease, followed by deterioration of the MRI picture – an increase in the heterogeneity of the structure of the pituitary gland, an increase in its size, signs of involvement of the chiasm and left optic nerve. Against the background of specific treatment, involution of radiologi-cal symptoms was noted.

Discussion. Autoimmune hypophysitis is an extremely rare disease with a polymorphic and nonspecific clinical and radiological picture. Changes on MRI of the pituitary gland can be detected at the onset of the disease, followed by identification of the MRI picture. The peculiarity of the presented clinical observation in the development of radiological symptoms from the onset of the disease "Auto-immune hypophysitis" against the background of ongoing treatment.

Conclusion. MRI is crucial in recognizing changes characteristic of pituitary pathology. In this clinical observation, the first symptom was heterogeneity of pituitary enhancement, which in combi-nation with a decrease in hormone levels, made it possible to suspect hypophysitis.

 

Keywords: autoimmune hypophysitis, magnetic resonance imaging, chiasmal-sellar region, pitu-itary gland.

 

 

Corresponding author: Pyshkina Yu.S., e-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript .

 

For citation: Surovcev E.N., Kapishnikov A.V., Pyshkina Yu.S., Palamarja S.A. Autoimmune hy-pophisitis: the role of magnetic resonance imaging in the diagnosis and monitoring of the disease. REJR 2023; 13(1):118-125. DOI: 10.21569/2222-7415-2023-13-1-118-125.

 

Received: 31.10.22

Аccepted: 19.01.23