MRI OF BONE MARROW FAT FRACTION: DIXON VS DIXON-QUANT

 

Tereshchenko G.V., Kriventsova N.A., Kuprianov D.A., Novichkova G.A.

 

Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology. Moscow, Russia.

D

ixon MRI sequences based on chemical shift are highly sensitive to the fat and water content in the tissue. If special sequence as mDixon-quant is not available then it may be necessary to rely on a basic, and more generally available, method for FF measurement by fat-to-water ratio.

Purpose. To evaluate the comparability and reliability of the commonly used MRI program designed for wide practical use (mDixon) and the new program with fat fraction maps (mDixon-quant).

Materials and methods. The study included 100 patients under 18 years of age with aplastic anemia (64%) and chronic myeloproliferative disorders (36%). The study was carried out at the Dmit-

 

ry Rogachev haematology, oncology and immunology centre on the Philips Achieva 3.0 T using standard mDixon and mDixon-quant with FF maps. FF measured in the ilium and lumbar vertebrae.

Results. There was no statistically significant difference between FF by the water-to-fat ratio on mDixon and on mDixon-quant FF maps. In addition, both methods showed a strong correlation (r>0.996, p<0.001), high reliability (ICC>0.996).

Conclusion. The mDixon and mDixon-quant fat fraction values are comparable and can be used to evaluate bone marrow in paediatric patients with haematological disorders.

 

Keywords: acute coronary syndrome, depression, fMRI.

 

Corresponding author: Kriventsova N.A., e-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript

 

For citation: Tereshchenko G.V., Kriventsova N.A., Kuprianov D.A., Novichkova G.A. MRI of bone marrow fat fraction: Dixon vs Dixon-quant. REJR 2023; 13(4):92-100. DOI: 10.21569/2222-7415-2023-13-4-92-100.

Received:        07.07.23 Accepted:       07.11.23