Kirilenko N.A.1,3, Zyablova E.I.2,3, Agurina N.V.2,3, Voronova I.G.2,3


1 – Specialized Clinical Infectious Hospital.

2 – Scientific Research Institute – S.V. Ochapovskiy Krasnodar Regional Clinical Hospital Number 1.

3 – Kuban State Medical University. Krasnodar, Russia.


nalysis of a clinical case of a new coronavirus infection, complicated by the spread of the fungal agent Aspergillus, which occurs with damage to the respiratory organs and bones of the facial skeleton, which is associated with the diagnostic capabilities of computed tomography.

Materials and methods. A clinical case of a 62-year-old patient with complaints of weakness, malaise, dry cough and fever, followed by follow-up of a condition that required hospitalization in an infectious diseases hospital. Computed tomography revealed polysegmental destructive pneumonia, as well as osteomyelitis of the facial bones.

Results. The diagnosis of Aspergillus osteomyelitis of the facial bones was suggested on the basis of computed tomography data (together with changes in the lungs) and confirmed by examination of biomaterial. In the infectious diseases hospital, the patient received antibacterial and antifungal therapy and was discharged with improvement in the underlying disease (new coronavirus infection COVID-19, complicated by polysegmental destructive pneumonia) with a recommendation for further surgical treatment in a maxillofacial surgery hospital. In the department of maxillofacial surgery of the emergency hospital, an operation was performed in the form of resection of the facial skeleton bones.

Discussion. Coronavirus infection COVID-19 can occur with various complications, including such rare ones as osteomyelitis of the facial bones caused by Aspergillus. While establishing a diagnosis, in addition to clinical examination, computed tomography plays a key role, as well as histological verification.

Conclusion. Computed tomography is a highly informative diagnostic method for patients with osteomyelitis of the maxillofacial region, which makes it possible to clarify the location, severity and extent of the lesion which affects further patient management tactics.



Keywords: COVID-19, aspergillosis, complication, osteomyelitisof facial bones.


Corresponding author: Kirilenko N.A., е-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript


For citation: Kirilenko N.A., Zyablova E.I., Agurina N.V., Voronova I.G. A clinical case of osteomyelitis of the maxillofacial region in a patient with COVID-19. REJR 2023; 13(4):110-119. DOI: 10.21569/2222-7415-2023-13-4-110-119.

Received:        28.10.23                 Accepted:       07.11.23