COHORT COMPARATIVE STUDY OF COVID-19 VACCINATED AND NON-VACCINATED PATIENTS DEPENDING ON CT CHEST FINDINGS BETWEEN IRAQI
AND JORDANIAN POPULATION
Shaymaa Khalid Abdulqader1, Fadi Faisal Anwer Ali2, Ghasaq Ma'an Bakr3,
Lubna Hasan Najm4, Hebah Fayiz Ahmad AlHadidi5,
Reem Taleb Amer Khallaf2, Mortadha Al-Kinani6
1 - Department of Radiology, Al-Kindy College of Medicine, University of Baghdad. Baghdad, Iraq.
2 - Department of Radiology, Almaqasid Charity Hospital. Amman, Jordan.
3 - Department of Radiology, College of Medicine, Diyala University. Diyala, Iraq.
4 - Department of Radiology, Renal Disease and Transplant Center, Medical City. Baghdad, Iraq.
5 - Quality and Infection Department, Almaqasid Charity Hospital. Amman, Jordan.
6 - The University of Texas Southwestern Medical Center: Dallas. Texas, US.
|
S |
ince the beginning of the COVID-19 pandemic, it has recorded more than 9 million deaths globally as one of the major health crises of this century. This study aimed to compare chest CT properties of COVID-19 infection in vaccinated and non-vaccinated cases by multi-radiologist readers and to evaluate the radiologist's performance in differentiation between these two conditions.
Materials and Methods. A retrospective study was conducted at the Department of Radiology, Al-Kindy Teaching Hospital, Iraq, and the Department of Radiology, Almaqasid Charity Hospital, Jordon from 1st of March 2021 to 1st of December 2022. Nine hundred fifty-one patients were enrolled in this work (400 Jordanian cases and 551 Iraqi cases). Those were diagnosed with COVID-19, which that proven by both chest CT scans and PCR tests.
Results. All groups were significantly different in terms of mean age (p <0.00001) and sex (p = 0.0036). There was a significant difference among vaccine types utilized (p = 0.0022The most common CT scan finding was GGO in all groups with statistically significant differences (p<0.00001). Concerning grouping of CT scores, the findings reported that the majority of vaccinated cases of both nations were located at and below 50% of CT score severity of COVID-19 without difference (p=0.055), this could be due to the efficacy of vaccination. However, compared non-vaccinated patients from both nations, revealed that most of the cases lie at mid-score and above with no significant difference (p=0.639). When dealing with survival, the mortality, and crude death rate among Iraqi vaccinated cases were better than Iraqi non-vaccinated people. In Jordanian vaccinated cases, the mortality rate was zero. In the univariate model, the severity of COVID-19 was seen in elderly, females, and unvaccinated with ground-glass opacification (GGO) of chest CT scan whereas female gender and non-vaccinated status were significant predictors for death in multivariate analysis.
Conclusion. CT scan score may be suitable to assess COVID-19 severity and outcome. Mean old age, female sex and vaccine types could be predictors of COVID pneumonia. The most common CT scan finding was GGO. CT score threshold in vaccinated cases is lower than in non-vaccinated cases. The mortality and crude death rate among Iraqi vaccinated cases were lower than non-vaccinated people. In Jordanian vaccinated cases, the death rates are lower than non-vaccinated peoples. Female gender and unvaccinated groups are the most predictor factors to poor outcomes of disease. These data can help physicians guide management strategies for COVID-19.
Keywords: COVID-19, CT scan score, score threshold, pneumonia, coronavirus.
Corresponding author: Shaymaa Khalid Abdulqader, e-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript
For citation: Shaymaa Khalid Abdulqader, Fadi Faisal Anwer Ali, Ghasaq Ma'an Bakr, Lubna Hasan Najm, Hebah Fayiz Ahmad AlHadidi, Reem Taleb Amer Khallaf, Mortadha Al-Kinani. Cohort comparative study of COVID-19 vaccinated and non-vaccinated patients depending on CT chest findings between Iraqi and jordanian population. REJR 2024; 14(1):5-15. DOI: 10.21569/2222-7415-
2024-14-1-5-15.
Received: 20.01.24 Accepted: 25.01.24