A RARE CASE OF ATYPICAL TERATOID RHABDOID TUMOR OF CENTRAL NERVOUS SYSTEM

 

Gorshkova V.I.1, Talybov R.S.2, Mochalov V.V.1, Trofimova T.N.3, Kleschevnikova T.M.1

 

1 - Regional Clinical Hospital №2. Tyumen, Russia.

2 - Tyumen State Medical University. Tyumen, Russia.

3 - The Pavlov First Saint Petersburg State Medical University. Saint Petersburg, Russia.

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D

emonstration of a clinical case and the capabilities of a multiparametric MRI mapping protocol in a rare embryonal tumor of the posterior cranial fossa diagnosis.

Material and methods. The clinical case of atypical teratoid-rhabdoid tumor in a patient A., 5 years old, is presented. An ultra-high-field MRI system (3 Tesla) was used and routine 5 mm slice thickness scanning was performed with the protocol of T1, T2, FLAIR, DWI pulse sequences and three-dimensional MPRAGE sequence with a slice thickness of 1.0 mm. The MRI examination protocol was complemented by highly specialized sequences: DSC-T2* perfusion, SWI and contrast enhancement.

Results. Based on the results of radiological diagnostic methods, a malignant tumor in the posterior cranial fossa was confirmed. The diagnosis was verified using histological and immunohistochemistry methods.

Discussion. The extremely rare extra-axial localization does not exclude the possibility of an atypical teratoid-rhabdoid tumor diagnosis. Features of atypical teratoid-rhabdoid tumor are radiological findings, an aggressive course of the disease with early postoperative progression.

Conclusion. The presented clinical observation demonstrates the importance of a comprehensive interdisciplinary approach using clinical, radiological, histological and immunohistochemical data for the timely diagnosis of embryonal tumor in order to make a tactical decision on combined treatment.

 

Keywords: atypical teratoid-rhabdoid tumor, multiparametric MRI mapping, interdisciplinary approach.

 


Corresponding author: Talybov R.S., e-mail: Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript

 

For citation: Gorshkova V.I., Talybov R.S., Mochalov V.V., Trofimova T.N., Kleschevnikova T.M. A rare case of atypical teratoid rhabdoid tumor of central nervous system. REJR 2024; 14(4):204-213. DOI: 10.21569/2222-7415-2024-14-4-204-213.

Received:        01.07.24                 Accepted: 10.10.24