Travina M.L.1, Popov A.G.2, Murtazalieva A.A.1

1-Scientific Center of Children’s Health. Moscow, Russia.

2-Medical Centre "FAMILY WORLD". St. Petersburg, Russia.

Purpose. The objective of the study was to analyze the diagnostic challenges and therapeutic specificity associated with treating isolated primary breast tuberculosis.

Materials and methods. Data of comprehensive physical examination including instrumental and laboratory examination methods in a patient with the isolated primary tuberculosis was presented.

Results. Primary breast tuberculosis was diagnosed in a 27 year-old woman after lactation. The patient was diagnosed when the puncture revealed multi-nucleated giant cells (Langhans' giant cells/Pirogov-Langhans cells). Administered specific treatment for a period of 4 months resulted in complete regression of the breast disease.

Conclusions. In case of absence of positive clinical dynamics in the treatment of breast inflammation differential diagnosis is required to exclude inflammatory breast cancer and tuberculosis. Negative reactions to Mantoux test/ PPD test and Diaskin-test/ DST can occur in the setting of the primary site of tuberculosis in breast. Targeting chemotherapy is effective in the treatment of breast tuberculosis. Screening for tuberculosis of patient’s close contacts can be recommended.


Keywords: breast (mammary) tuberculosis, mastitis, chronic inflammation, inflammatory breast cancer.


Corresponding author:  Travina M. L., Этот e-mail адрес защищен от спам-ботов, для его просмотра у Вас должен быть включен Javascript .


For citation: Travina M. L., Popov A. G., Murtazalieva A. A. Primary breast tuberculosis: case study. REJR. 2016; 6 (3):123-127. DOI:10.21569/2222-7415-2016-6-3-123-127.


Received: 22.06.2016 Accepted: 06.07.2016